Oral therapy of erectile dysfunction.
Why to wait one hour ?

C. Pérez-Martinez, I.B. Vargas-Diaz (Chihuahua, Mexico)


SUMMARY :

Since public use of sildenafil for oral therapy of ED, 60 minutes of waiting was invoked for start the effect in this inhibitor of phosphodiesterases type 5 in Latin patients.

Goal : The aim of this study is to show the time of start of effect of sildenafil
in patients under study for ED, using the Rigiscan test as part of the protocol of study, in an impotence clinic to identificate when start the effect on Latin males.

Material and method : Twenty-tree patients with ED were studied, only were included patients with IIEF-5 score equal or less than 21. Patients arrived to test of Rigiscan, with last meal ate at last two hour ago.
All tests were performed by the same nurse using Rigiscan plus device, in a special designed laboratory inside of a clinic of impotence by a modality provocative audiovisual sildenafil diurnal.
After basal test, each patient takes 50 mg of sildenafil and the test goon by at last 50 minutes more. All patients with cardiovascular disease were excluded.
For the analysis of start of effect we had used the technique of the best erection.

Results : We observed response in all 23 patients in an average timeof 26 minutes 30 seconds (min. 10 minutes, max. 49 minutes).

Conclusions : Is a general idea to prescribe sildenafil and recommend patients waitat last one our. This study showed that when patient with stomach partially empty take sildenafil, the beginning of effect could be as soon as 10 minutes, yet in a hostile place as the doctor’s office. This data can help to recommend take the first doses far as two hours from the last meal to get better results in ED therapy using sildenafil.
Most patients can see the beginning of effect in an average of 26 minutes from intake of sildenafil.

Key words :
o Impotence
o RigiScan
o Fast Provocative Audiovisual Test
o Sildenafil



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