Sildenafil as a first-step non-invasive diagnostic and therapeutic mean for male sexual dysfunction

P. Perimenis, K. Giannitsas, K. Gyftopoulos, A. Athanasopoulos, G. Barbalias (Patras, Grèce)


SUMMARY :

There are different simple or complicated diagnostic procedures for male sexual dysfunction. The semi- invasive and invasive ways include intracavernous injections of vasoactive drugs. We assessed the efficacy of sildenafil as a first- step non- invasive diagnostic and therapeutic tool for sexual dysfunction (SD) in an unselected male population. Sildenafil in titrating doses up to 100 mg was given to 61 consecutive men presenting to a sexual dysfunction clinic with medically documented ED and no contraindication. They had not undergone any specific diagnostic test before starting sildenafil. Of the 61 men, 33 (54.1 %) responded to sildenafil.

Twelve of the responders, representing 19.7 % of all studied men, proved to have pure psychogenic dysfunction and were discharged achieving spontaneous erections in a mean follow- up of 8.2 months. Men with no medical history, with multiple sclerosis, with hypertension and with mild coronary artery disease responded better. The response to sildenafil rate revealed that 54.1 % of men with sexual dysfunction do not need invasive diagnostic tests ; this fact reduces the overall cost of the diagnostic investigation. Sildenafil might be prescribed safely and effectively by non- urologists or in the primary care sector in cases with no significant medical history or in men with hypertension or mild coronary artery disease or multiple sclerosis.

Key words :
o Sexual
dysfunction
o Male impotence
o Sildenafil



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